HSPH1 anticorps (AA 653-858)

N° du produit ABIN6654098

Cet anticorps anti-HSPH1 est un anticorps Lapin Polyclonal détectant HSPH1 dans WB et ELISA. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour HSPH1 anticorps (AA 653-858) (ABIN6654098)

Antigène: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSPH1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-HSPH1 anticorps

Épitope: AA 653-858

Purification: Antigen affinity purified

Immunogène: Human Heat Shock Protein 105 recombinant protein (amino acids Y653-D858) was used as the immunogen for the HSP105 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the HSP105 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (human recombinant protein)

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the HSP105 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur HSPH1

Antigène: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Autre désignation: HSP105

Sujet: HSP105 (HEAT-SHOCK 105/110-KD PROTEIN 1), also called HSPH1 or HSP110, is a protein that in humans is encoded by the HSPH1 gene. Immunohistochemical analysis localizes HSP105 mainly in the cytoplasm. Database analysis indicates that both HSP105 isoforms are highly conserved during evolution. By analysis of radiation hybrids and human/rodent hybrid cell lines, the HSPH1 gene is mapped to chromosome 13. Both HSP105-alpha and HSP105-beta are upregulated in HeLa cells exposed to heat shock. HSP105-alpha, but not HSP105-beta, is also upregulate in response to other cell stresses. Following heat shock, HSP105 relocalizes from a cytoplasmic to perinuclear position. Besides, HSP110 may thus constitute a major determinant for both prognosis and treatment response in colorectal cancer.

UniProt: Q92598